ProBiS-Fold approach for annotation of human structures from the AlphaFold database with no corresponding structure in the PDB to discover new druggable binding sites |
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报告人:Dusanka Janezic 报告时间:2023-11-10(周五) 14:00-16:00 报告地点:实验18楼418室 主持人:唐赟教授 简介:
As a full professor of Mathematics in Natural Sciences at the University of Primorska, Slovenia, Dušanka Janežič is widely regarded for her contributions to the field of molecular modeling and drug design. With two scientific books and over 130 original research papers and review articles, her work has garnered over 3000 pure citations in the Web of Science database, and she holds an h-index of 25. She also served as one of the Editors at the esteemed ACS Journal of Chemical Information and Modeling from 2001 to 2014. Her numerous academic achievements include being named Ambassador in Science of the Republic of Slovenia in 1999 and receiving the prestigious Republic of Slovenia state award in science, the Zois Award, in 2013 for her outstanding achievements in mathematics in natural sciences. She has a distinguished academic background, having been a Fulbright Scholar at the National Institutes of Health in Bethesda, Maryland, USA, and a Deutcher Akademicher Austauschdienst Fellow at the Technical University of Munich, Germany. Moreover, she is known for founding the molecular modeling research field in Slovenia, and her research group is ranked among the top research groups globally in the field. Her novel approaches and concepts in molecular modeling have gained significant recognition in the scientific community, and her current research interests include developing graph theory, predicting protein-protein and protein-ligand binding sites, biomolecular simulations, and their application to pharmaceutical research and drug development. Her contributions have helped enhance our understanding of complex biological systems and have the potential to improve drug discovery processes. |
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