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黄青春


黄青春  博士,教授   

Mail address: qchuang@ecust.edu.cn  

 

 个人简介 
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        黄青春博士,教授。2001年毕业于南京农业大学获植物病理学博士学位,同年进入华东理工大学药物化工研究所2003年晋升副教授;2009晋升教授;2011-2012美国普渡大学访问学者。现为中国生物化学与分子生物学会会员,上海市毒理学会理事

        主要从事杀菌剂化学生物学研究,包括药物化学、衍生合成、毒理与应用、病害生物学方面的研究。作为项目负责人,先后承担了国家自然科学基金项目1项、国家重点研发计划项目的子项目2项、国家科技支撑计划项目2项、上海市科技攻关重点1项和重大项目1项、上海市生物医药科技专项项目2项、以及上海市“科技创新行动计划”农业领域科技项目2项等研究。在J. Agric. Food Chem.Pest Manag. Sci.J. Phytopathol.Pestic. Biochem. Physiol.Crop Protection、Drug Chem. Toxicol.、Ecotox Environ SafeChemosphere 等同行业领域发表学术研究论文80篇,申请中国发明专利30项,PCT专利3项,获得国家发明专利授权16。曾获得的荣誉:国家教育部自然科学一等奖1次、华东理工大学校先进工作者1次、华东理工大学优秀研究生指导教师3次。 

 

研究方向 
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1、生物源或天然仿生杀菌剂的化学修饰与结构衍生、新型杀菌剂创制、及杀菌剂应用技术研究。


2、病原微生物致病因子及其胞外多糖或脂多糖等的组成分析、及其响应抗菌剂作用的致病机制。 

 

近期代表性成果
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1、最新代表性论文

1)Jialin Xu, Dongmei Yan, Yongjun Chen, Danni Cai, Fengcheng Huang, Lisong Zhu,Xianfei Zhang, Shaorong Luan*, Ciying Xiao, Qingchun Huang*

      Fungicidal activity of novel quinazolin-6-ylcarboxylates and mode of action on Botrytis cinerea

      Pest Management Science 2023, Under review (中科院一区)

2)Yongjun Chen, Dongmei Yan, Jialin Xu, Hui Xiong, Shaorong Luan, Ciying Xiao, Qingchun Huang*

      The importance of selecting crystal form for triazole fungicide tebuconazole to enhance its botryticidal activity. 

      Science of the Total Environment 2023, 854:158778. (中科院一区)

3)Yongjun Chen, Xuefeng Liu, Dongmei Yan, Jialin Xu, Shaorong Luan, Ciying Xiao, Qingchun Huang*.  

      Exposure to emamectin benzoate confers cytotoxic effects on human Molt-4 T-cells and possible ameliorative role of vitamin E and dithiothreitol. 

      Drug and Chemical Toxicology 2023, 46(3): 413-422. 

4)Xuefeng Liu, Yongjun Chen, Yunfei Deng, Ciying Xiao, Shaorong Luan,Qingchun Huang*.

      Novel galactosyl moiety-conjugated furylchalcones synthesized facilely display significant regulatory effect on plant growth.

       Journal of Agricultural and Food Chemistry 2022, 70(6): 1766–1775. (中科院一区)

5)Shaorong Luan, Yongjun Chen, Xiaohua Wang, Dongmei Yan, Jialin Xu, Hairong Cui,* Qingchun Huang*.

      Synergistic cooperation of pyraclostrobin and its co-formulants to improve fungicidal activity against Botrytis cinerea

       Pesticide Biochemistry and Physiology 2022, 188: 105287. (中科院一区)

6Dongmei Yan, Jialin Xu, Yongjun Chen, Qingchun Huang *

        The immunotoxicity of ten insecticides against insect hemocyte cells in vitro

      In Vitro Cellular & Developmental Biology - Animal 2022, 58(10): 912–921.


2、华东理工大学研究生优秀学位论文(研究生:熊惠,2021)

 1)Xui Xiong, Xuefeng Liu, Jiuyong Xu, Xianfei Zhang, Shaorong Luan, Qingchun Huang*.  

      Fungicidal effect of pyraclostrobin against Botrytis cinerea in relation to its crystal structure. 

      Journal of Agricultural and Food Chemistry 2020, 68: 10975–10983.(中科院一区)

2)Xui Xiong, Xuefeng Liu, Yuhang Fan, Shaorong Luan, Qingchun Huang*. 

      Effect of membrane integrity on survival competition of Botrytis cinerea upon QoI fungicide pyraclostrobin. 

      Journal of Phytopathology 2020, 168: 601–608

3)Xui Xiong, Xuefeng Liu, Jiuyong Xu, Xianfei Zhang, Song Cao, Qingchun Huang*.  

      Safety assessment of a new benzoylphenylurea TXH09 and its efficacy against two borers Ostrinia furnacalis and

      Grapholitha molesta in field. 

      Ecotoxicology and Environmental Safety 2020, 197: 110591. 

4Shaorong Luan, Xui Xiong, Solange Muhayimana, Jiuyong Xu, Xianfei Zhang, Fangfang Zhang, Xuefeng Liu, Yongjun Chen, Qingchun Huang*

      Accurate analysis of tricarboxylic acid cycle metabolites and anion components in hemocytes by IC-CD/ESI-MS for quantifying 

      insecticide impairment on cellular immunity in Mythimna separata

      Journal of Agricultural and Food Chemistry 2021, 69: 1984−1993.(中科院一区)

5)Jiuyong Xu, Xui Xiong, Xianfei Zhang, Solange Muhayimana, Xuefeng Liu, Yufan Xue, and Qingchun Huang*

      Comparative cytotoxic effects of five commonly used triazole alcohol fungicides on human cells of different tissue types. 

      Journal of Environmental Science and Health B. 202055(5): 438–446.  

6)Xianfei Zhang, Jiuyong Xu, Solange Muhayimana, Xui Xiong, Yufan Xue, Qingchun Huang*

      Effect of 3-(2-pyridyl)methyl-2-(4-chlorphenyl)iminothiazolidine applied as a new fungicide against benzimidazole-resistant 

      Sclerotinia sclerotiorum

      Pest Management Science 202076: 2978–2985.(中科院一区)

7)Solange Muhayimana, Xianfei Zhang, Jiuyong Xu, Xui Xiong, Shaorong Luan*, Qiqi Zhu, Qingchun Huang*.  

      Cytotoxic selectivity and apoptosis induction of piericidin A contributes potentially to its insecticidal effect against Mythimna 

      separata (Lepidoptera: Noctuidae) larvae. 

      Pesticide Biochemistry and Physiology 2019, 157: 1925

8)Xianghu Zhao, Chunmei LiJiuyong Xu, Xianfei Zhang, Xui Xiong, Qingchun Huang*, Song Cao* 

      Field-scale evaluation on the efficacy of a novel benzoylphenylurea TXH09 against chewing insect pests harming vegetables and rice

      Crop Protection 2019, 126: 104925.  


3、华东理工大学研究生优秀学位论文(研究生:郓新明,2018)

1)Xinming YunQingchun Huang*Wenbing Rao, Ciying Xiao, Tao Zang, Zhifan Mao, Ziyi Wan.

      A comparative assessment of cytotoxicity of commonly used agricultural insecticides to human and insect cells. 

      Ecotoxicology and Environmental Safety 2017, 137: 179–185.

2Xinming Yun, Wenbing Rao, Ciying Xiao, Qingchun Huang*

      Apoptosis of leukemia K562 and Molt-4 cells induced by emamectin benzoate involving mitochondrial membrane potential loss 

      and intracellular Ca2+ modulation. 

      Environmental Toxicology and Pharmacology 2017, 52: 280–287.  

3Qingchun Huang*Xinming Yun, Wenbing Rao, Ciying Xiao. 

      Antioxidative cellular response of lepidopteranovariancells to photoactivated alpha-terthienyl. 

      Pesticide Biochemistry and Physiology 2017, 137: 1–7

4Shaorong Luan, Wenbing RaoXinming Yun, Ciying Xiao, Zhikang Xu, Jialing Lang, Qingchun Huang*

      Emamectin benzoate induces ROS-mediated DNA damage and apoptosis in Trichoplusia Tn5B1-4 cells. 

      Chemico-Biological Interactions 2017, 273: 90–98.

5Qingchun Huang*, Lei Zhang, Chao Yang, Xinming Yun, Yuan He. 

      The competence of hemocyte immunity in the armyworm Mythimna separata larvae to sublethal hexaflumuron exposure. 

      Pesticide Biochemistry and Physiology 2016, 130: 31–38.


授权和公开发明专利

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喹唑啉基羧酸酯类化合物及其用途.201710809500.3

亚氨基噻唑烷类化合物的新用途.201710140803.0

分离纯化昆虫谷氨酰胺转氨酶的方法.201610458931.5

一种新型昆虫细胞免疫抑制剂的用途.201610301431.0

用于制备昆虫神经元细胞的生理缓冲液、消解液及方法.201410025109.0

阿维菌素B1a荧光标记物及其应用.201410025107.1

用于检测油菜菌核病菌的方法和培养基.201310564218.5

含七氟异丙基苯甲酰脲类化合物及其用途.101538227B

2’-羟基六氟异丙基的邻苯二甲酰胺类化合物及其用途.102320998

新型3-硒代吲哚的合成对植物生长促进和富硒作用.101117329B 

含二氟(亚)甲基邻甲酰胺基苯甲酰胺类化合物.102617551A

具有杀虫活性的含氮杂环化合物、其制备及用途.PCT/CN2008/071115

一类具有高杀虫活性化合物的制备方法及用途.PCT/CN 2006/000360

唑酰胺类化合物及其制备和应用.200310108478.8

一类新型3-硒代吲哚的合成对植物生长促进和富硒作用.200610029737. 1

一种噁唑哒嗪及其衍生物的剂型与应用.200410017164.1

哌嗪衍生物及其用途.200710045661.6

腺苷衍生物及其用途.201510022902.X

Nitrogenous heterocyclic compounds with insecticidal activity, and the preparation and use thereof.    美国专利US 12/864,410

Benzoylurea compounds bearing heptafluoroisopropyl and uses thereof. PCT专利WO/2009/115040 A1

硝基亚甲基衍生物及其用途.PCT/CN2005/000617,WO05745204.7,US11/751,836,EP1826209A1,JP2007-541642 

 

热忱欢迎研究生加入杀菌剂和抗肿瘤药的创新研究队伍

网页发布时间: 2014-03-26