黄青春  博士,教授   

Mail address: qchuang@ecust.edu.cn  

 个人简介 
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        黄青春，博士，教授。2001年毕业于南京农业大学获植物病理学博士学位，同年进入华东理工大学药物化工研究所。2003年晋升副教授；2009年晋升教授；2011年-2012年美国普渡大学访问学者。现为中国生物化学与分子生物学会会员，上海市毒理学会理事。

        主要从事杀菌剂化学生物学研究，包括药物化学、衍生合成、毒理与应用、病害生物学等方面的研究。作为项目负责人，先后承担了国家自然科学基金项目1项、国家重点研发计划项目的子项目2项、国家科技支撑计划项目2项、上海市科技攻关重点1项和重大项目1项、上海市生物医药科技专项项目2项、以及上海市“科技创新行动计划”农业领域科技项目2项等研究。在J. Agric. Food Chem.、Pest Manag. Sci.、J. Phytopathol.、Pestic. Biochem. Physiol.、Crop Protection、Drug Chem. Toxicol.、Ecotox Environ Safe、Chemosphere 等同行业领域发表学术研究论文80余篇，申请中国发明专利30余项，PCT专利3项，获得国家发明专利授权16项。曾获得的荣誉：国家教育部自然科学一等奖1次、华东理工大学校先进工作者1次、华东理工大学优秀研究生指导教师3次。 

研究方向 
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1、生物源或天然仿生杀菌剂的化学修饰与结构衍生、新型杀菌剂创制、及杀菌剂应用技术研究。

2、病原微生物致病因子及其胞外多糖或脂多糖等的组成分析、及其响应抗菌剂作用的致病机制。 

近期代表性成果
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1、最新代表性论文

1）Jialin Xu, Dongmei Yan, Yongjun Chen, Danni Cai, Fengcheng Huang, Lisong Zhu,Xianfei Zhang, Shaorong Luan^*, Ciying Xiao, Qingchun Huang^*. 

      Fungicidal activity of novel quinazolin-6-ylcarboxylates and mode of action on Botrytis cinerea. 

      Pest Management Science 2023, Under review （中科院一区）

2）Yongjun Chen, Dongmei Yan, Jialin Xu, Hui Xiong, Shaorong Luan^⁎, Ciying Xiao, Qingchun Huang^*. 

      The importance of selecting crystal form for triazole fungicide tebuconazole to enhance its botryticidal activity. 

      Science of the Total Environment 2023, 854:158778. （中科院一区）

^{3）Yongjun Chen, Xuefeng Liu, Dongmei Yan, Jialin Xu, Shaorong Luan, Ciying Xiao, Qingchun Huang*.}  

      Exposure to emamectin benzoate confers cytotoxic effects on human Molt-4 T-cells and possible ameliorative role of vitamin E and dithiothreitol. 

      ^{Drug and Chemical Toxicology 2023, 46(3): 413-422.} 

4）Xuefeng Liu, Yongjun Chen, Yunfei Deng, Ciying Xiao, Shaorong Luan,^* Qingchun Huang^*.

      Novel galactosyl moiety-conjugated furylchalcones synthesized facilely display significant regulatory effect on plant growth.

       Journal of Agricultural and Food Chemistry 2022, 70(6): 1766–1775. （中科院一区）

5）Shaorong Luan, Yongjun Chen, Xiaohua Wang, Dongmei Yan, Jialin Xu, Hairong Cui,* Qingchun Huang^*.

      Synergistic cooperation of pyraclostrobin and its co-formulants to improve fungicidal activity against Botrytis cinerea. 

       Pesticide Biochemistry and Physiology 2022, 188: 105287. （中科院一区）

6）Dongmei Yan, Jialin Xu, Yongjun Chen, Qingchun Huang ^*

        ^{The immunotoxicity of ten insecticides against insect hemocyte cells in vitro.} 

      ^{In Vitro Cellular & Developmental Biology - Animal 2022, 58(10): 912–921.}

2、华东理工大学研究生优秀学位论文（研究生：熊惠，2021）

 1）Xui Xiong, Xuefeng Liu, Jiuyong Xu, Xianfei Zhang, Shaorong Luan, Qingchun Huang^*.  

      Fungicidal effect of pyraclostrobin against Botrytis cinerea in relation to its crystal structure. 

      Journal of Agricultural and Food Chemistry 2020, 68: 10975–10983.（中科院一区）

2）Xui Xiong, Xuefeng Liu, Yuhang Fan, Shaorong Luan, Qingchun Huang^*. 

      Effect of membrane integrity on survival competition of Botrytis cinerea upon QoI fungicide pyraclostrobin. 

      Journal of Phytopathology 2020, 168: 601–608. 

3）Xui Xiong, Xuefeng Liu, Jiuyong Xu, Xianfei Zhang, Song Cao, Qingchun Huang^*.  

      Safety assessment of a new benzoylphenylurea TXH09 and its efficacy against two borers Ostrinia furnacalis and

      Grapholitha molesta in field. 

      Ecotoxicology and Environmental Safety 2020, 197: 110591. 

4）Shaorong Luan, Xui Xiong, Solange Muhayimana, Jiuyong Xu, Xianfei Zhang, Fangfang Zhang, Xuefeng Liu, Yongjun Chen, Qingchun Huang^*. 

      Accurate analysis of tricarboxylic acid cycle metabolites and anion components in hemocytes by IC-CD/ESI-MS for quantifying 

      insecticide impairment on cellular immunity in Mythimna separata. 

      Journal of Agricultural and Food Chemistry 2021, 69: 1984−1993.（中科院一区）

5）Jiuyong Xu, Xui Xiong, Xianfei Zhang, Solange Muhayimana, Xuefeng Liu, Yufan Xue, and Qingchun Huang^*. 

      Comparative cytotoxic effects of five commonly used triazole alcohol fungicides on human cells of different tissue types. 

      Journal of Environmental Science and Health B. 2020, 55(5): 438–446.  

6）Xianfei Zhang, Jiuyong Xu, Solange Muhayimana, Xui Xiong, Yufan Xue, Qingchun Huang^*. 

      Effect of 3-(2-pyridyl)methyl-2-(4-chlorphenyl)iminothiazolidine applied as a new fungicide against benzimidazole-resistant 

      Sclerotinia sclerotiorum. 

      Pest Management Science 2020, 76: 2978–2985.（中科院一区）

7）Solange Muhayimana, Xianfei Zhang, Jiuyong Xu, Xui Xiong, Shaorong Luan^*, Qiqi Zhu, Qingchun Huang^*.  

      Cytotoxic selectivity and apoptosis induction of piericidin A contributes potentially to its insecticidal effect against Mythimna 

      separata (Lepidoptera: Noctuidae) larvae. 

      Pesticide Biochemistry and Physiology 2019, 157: 19–25. 

8）Xianghu Zhao, Chunmei Li, Jiuyong Xu, Xianfei Zhang, Xui Xiong, Qingchun Huang^*, Song Cao^*.  

      Field-scale evaluation on the efficacy of a novel benzoylphenylurea TXH09 against chewing insect pests harming vegetables and rice. 

      Crop Protection 2019, 126: 104925.  

3、华东理工大学研究生优秀学位论文（研究生：郓新明，2018）

1）Xinming Yun, Qingchun Huang^*, Wenbing Rao, Ciying Xiao, Tao Zang, Zhifan Mao, Ziyi Wan.

      A comparative assessment of cytotoxicity of commonly used agricultural insecticides to human and insect cells. 

      Ecotoxicology and Environmental Safety 2017, 137: 179–185.

2）Xinming Yun, Wenbing Rao, Ciying Xiao, Qingchun Huang^*. 

      Apoptosis of leukemia K562 and Molt-4 cells induced by emamectin benzoate involving mitochondrial membrane potential loss 

      and intracellular Ca²⁺ modulation. 

      Environmental Toxicology and Pharmacology 2017, 52: 280–287.  

3）Qingchun Huang^*, Xinming Yun, Wenbing Rao, Ciying Xiao. 

      Antioxidative cellular response of lepidopteranovariancells to photoactivated alpha-terthienyl. 

      Pesticide Biochemistry and Physiology 2017, 137: 1–7. 

4）Shaorong Luan, Wenbing Rao, Xinming Yun, Ciying Xiao, Zhikang Xu, Jialing Lang, Qingchun Huang^*. 

      Emamectin benzoate induces ROS-mediated DNA damage and apoptosis in Trichoplusia Tn5B1-4 cells. 

      Chemico-Biological Interactions 2017, 273: 90–98.

5）Qingchun Huang^*, Lei Zhang, Chao Yang, Xinming Yun, Yuan He. 

      The competence of hemocyte immunity in the armyworm Mythimna separata larvae to sublethal hexaflumuron exposure. 

      Pesticide Biochemistry and Physiology 2016, 130: 31–38.

授权和公开发明专利

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喹唑啉基羧酸酯类化合物及其用途.201710809500.3

亚氨基噻唑烷类化合物的新用途.201710140803.0

分离纯化昆虫谷氨酰胺转氨酶的方法.201610458931.5

一种新型昆虫细胞免疫抑制剂的用途.201610301431.0

用于制备昆虫神经元细胞的生理缓冲液、消解液及方法.201410025109.0

用于检测油菜菌核病菌的方法和培养基.201310564218.5

Nitrogenous heterocyclic compounds with insecticidal activity, and the preparation and use thereof.    美国专利US 12/864,410