
黄青春 博士,教授
Mail address: qchuang@ecust.edu.cn
个人简介
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黄青春,博士,教授。2001年毕业于南京农业大学获植物病理学博士学位,同年进入华东理工大学药物化工研究所。2003年晋升副教授;2009年晋升教授;2011年-2012年美国普渡大学访问学者。现为中国生物化学与分子生物学会会员,上海市毒理学会理事。
主要从事杀菌剂化学生物学研究,包括药物化学、衍生合成、毒理与应用、病害生物学等方面的研究。作为项目负责人,先后承担了国家自然科学基金项目1项、国家重点研发计划项目的子项目2项、国家科技支撑计划项目2项、上海市科技攻关重点1项和重大项目1项、上海市生物医药科技专项项目2项、以及上海市“科技创新行动计划”农业领域科技项目2项等研究。在J. Agric. Food Chem.、Pest Manag. Sci.、J. Phytopathol.、Pestic. Biochem. Physiol.、Crop Protection、Drug Chem. Toxicol.、Ecotox Environ Safe、Chemosphere 等同行业领域发表学术研究论文80余篇,申请中国发明专利30余项,PCT专利3项,获得国家发明专利授权16项。曾获得的荣誉:国家教育部自然科学一等奖1次、华东理工大学校先进工作者1次、华东理工大学优秀研究生指导教师3次。
研究方向
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1、生物源或天然仿生杀菌剂的化学修饰与结构衍生、新型杀菌剂创制、及杀菌剂应用技术研究。
2、病原微生物致病因子及其胞外多糖或脂多糖等的组成分析、及其响应抗菌剂作用的致病机制。
近期代表性成果
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1、最新代表性论文
1)Jialin Xu, Dongmei Yan, Yongjun Chen, Danni Cai, Fengcheng Huang, Lisong Zhu,Xianfei Zhang, Shaorong Luan*, Ciying Xiao, Qingchun Huang*.
Fungicidal activity of novel quinazolin-6-ylcarboxylates and mode of action on Botrytis cinerea.
Pest Management Science 2023, Under review (中科院一区)
2)Yongjun Chen, Dongmei Yan, Jialin Xu, Hui Xiong, Shaorong Luan⁎, Ciying Xiao, Qingchun Huang*.
The importance of selecting crystal form for triazole fungicide tebuconazole to enhance its botryticidal activity.
Science of the Total Environment 2023, 854:158778. (中科院一区)
3)Yongjun Chen, Xuefeng Liu, Dongmei Yan, Jialin Xu, Shaorong Luan, Ciying Xiao, Qingchun Huang*.
Exposure to emamectin benzoate confers cytotoxic effects on human Molt-4 T-cells and possible ameliorative role of vitamin E and dithiothreitol.
Drug and Chemical Toxicology 2023, 46(3): 413-422.
4)Xuefeng Liu, Yongjun Chen, Yunfei Deng, Ciying Xiao, Shaorong Luan,* Qingchun Huang*.
Novel galactosyl moiety-conjugated furylchalcones synthesized facilely display significant regulatory effect on plant growth.
Journal of Agricultural and Food Chemistry 2022, 70(6): 1766–1775. (中科院一区)
5)Shaorong Luan, Yongjun Chen, Xiaohua Wang, Dongmei Yan, Jialin Xu, Hairong Cui,* Qingchun Huang*.
Synergistic cooperation of pyraclostrobin and its co-formulants to improve fungicidal activity against Botrytis cinerea.
Pesticide Biochemistry and Physiology 2022, 188: 105287. (中科院一区)
6)Dongmei Yan, Jialin Xu, Yongjun Chen, Qingchun Huang *
The immunotoxicity of ten insecticides against insect hemocyte cells in vitro.
In Vitro Cellular & Developmental Biology - Animal 2022, 58(10): 912–921.
2、华东理工大学研究生优秀学位论文(研究生:熊惠,2021)
1)Xui Xiong, Xuefeng Liu, Jiuyong Xu, Xianfei Zhang, Shaorong Luan, Qingchun Huang*.
Fungicidal effect of pyraclostrobin against Botrytis cinerea in relation to its crystal structure.
Journal of Agricultural and Food Chemistry 2020, 68: 10975–10983.(中科院一区)
2)Xui Xiong, Xuefeng Liu, Yuhang Fan, Shaorong Luan, Qingchun Huang*.
Effect of membrane integrity on survival competition of Botrytis cinerea upon QoI fungicide pyraclostrobin.
Journal of Phytopathology 2020, 168: 601–608.
3)Xui Xiong, Xuefeng Liu, Jiuyong Xu, Xianfei Zhang, Song Cao, Qingchun Huang*.
Safety assessment of a new benzoylphenylurea TXH09 and its efficacy against two borers Ostrinia furnacalis and
Grapholitha molesta in field.
Ecotoxicology and Environmental Safety 2020, 197: 110591.
4)Shaorong Luan, Xui Xiong, Solange Muhayimana, Jiuyong Xu, Xianfei Zhang, Fangfang Zhang, Xuefeng Liu, Yongjun Chen, Qingchun Huang*.
Accurate analysis of tricarboxylic acid cycle metabolites and anion components in hemocytes by IC-CD/ESI-MS for quantifying
insecticide impairment on cellular immunity in Mythimna separata.
Journal of Agricultural and Food Chemistry 2021, 69: 1984−1993.(中科院一区)
5)Jiuyong Xu, Xui Xiong, Xianfei Zhang, Solange Muhayimana, Xuefeng Liu, Yufan Xue, and Qingchun Huang*.
Comparative cytotoxic effects of five commonly used triazole alcohol fungicides on human cells of different tissue types.
Journal of Environmental Science and Health B. 2020, 55(5): 438–446.
6)Xianfei Zhang, Jiuyong Xu, Solange Muhayimana, Xui Xiong, Yufan Xue, Qingchun Huang*.
Effect of 3-(2-pyridyl)methyl-2-(4-chlorphenyl)iminothiazolidine applied as a new fungicide against benzimidazole-resistant
Sclerotinia sclerotiorum.
Pest Management Science 2020, 76: 2978–2985.(中科院一区)
7)Solange Muhayimana, Xianfei Zhang, Jiuyong Xu, Xui Xiong, Shaorong Luan*, Qiqi Zhu, Qingchun Huang*.
Cytotoxic selectivity and apoptosis induction of piericidin A contributes potentially to its insecticidal effect against Mythimna
separata (Lepidoptera: Noctuidae) larvae.
Pesticide Biochemistry and Physiology 2019, 157: 19–25.
8)Xianghu Zhao, Chunmei Li, Jiuyong Xu, Xianfei Zhang, Xui Xiong, Qingchun Huang*, Song Cao*.
Field-scale evaluation on the efficacy of a novel benzoylphenylurea TXH09 against chewing insect pests harming vegetables and rice.
Crop Protection 2019, 126: 104925.
3、华东理工大学研究生优秀学位论文(研究生:郓新明,2018)
1)Xinming Yun, Qingchun Huang*, Wenbing Rao, Ciying Xiao, Tao Zang, Zhifan Mao, Ziyi Wan.
A comparative assessment of cytotoxicity of commonly used agricultural insecticides to human and insect cells.
Ecotoxicology and Environmental Safety 2017, 137: 179–185.
2)Xinming Yun, Wenbing Rao, Ciying Xiao, Qingchun Huang*.
Apoptosis of leukemia K562 and Molt-4 cells induced by emamectin benzoate involving mitochondrial membrane potential loss
and intracellular Ca2+ modulation.
Environmental Toxicology and Pharmacology 2017, 52: 280–287.
3)Qingchun Huang*, Xinming Yun, Wenbing Rao, Ciying Xiao.
Antioxidative cellular response of lepidopteranovariancells to photoactivated alpha-terthienyl.
Pesticide Biochemistry and Physiology 2017, 137: 1–7.
4)Shaorong Luan, Wenbing Rao, Xinming Yun, Ciying Xiao, Zhikang Xu, Jialing Lang, Qingchun Huang*.
Emamectin benzoate induces ROS-mediated DNA damage and apoptosis in Trichoplusia Tn5B1-4 cells.
Chemico-Biological Interactions 2017, 273: 90–98.
5)Qingchun Huang*, Lei Zhang, Chao Yang, Xinming Yun, Yuan He.
The competence of hemocyte immunity in the armyworm Mythimna separata larvae to sublethal hexaflumuron exposure.
Pesticide Biochemistry and Physiology 2016, 130: 31–38.
授权和公开发明专利
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喹唑啉基羧酸酯类化合物及其用途.201710809500.3
亚氨基噻唑烷类化合物的新用途.201710140803.0
分离纯化昆虫谷氨酰胺转氨酶的方法.201610458931.5
一种新型昆虫细胞免疫抑制剂的用途.201610301431.0
用于制备昆虫神经元细胞的生理缓冲液、消解液及方法.201410025109.0
阿维菌素B1a荧光标记物及其应用.201410025107.1
用于检测油菜菌核病菌的方法和培养基.201310564218.5
含七氟异丙基苯甲酰脲类化合物及其用途.101538227B
含2’-羟基六氟异丙基的邻苯二甲酰胺类化合物及其用途.102320998
新型3-硒代吲哚的合成对植物生长促进和富硒作用.101117329B
含二氟(亚)甲基邻甲酰胺基苯甲酰胺类化合物.102617551A
具有杀虫活性的含氮杂环化合物、其制备及用途.PCT/CN2008/071115
一类具有高杀虫活性化合物的制备方法及用途.PCT/CN 2006/000360
唑酰胺类化合物及其制备和应用.200310108478.8
一类新型3-硒代吲哚的合成对植物生长促进和富硒作用.200610029737. 1
一种噁唑哒嗪及其衍生物的剂型与应用.200410017164.1
哌嗪衍生物及其用途.200710045661.6
腺苷衍生物及其用途.201510022902.X
Nitrogenous heterocyclic compounds with insecticidal activity, and the preparation and use thereof. 美国专利US 12/864,410
Benzoylurea compounds bearing heptafluoroisopropyl and uses thereof. PCT专利WO/2009/115040 A1
硝基亚甲基衍生物及其用途.PCT/CN2005/000617,WO05745204.7,US11/751,836,EP1826209A1,JP2007-541642
热忱欢迎研究生加入杀菌剂和抗肿瘤药的创新研究队伍