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陶黎明



陶黎明 博士 教授 

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电话:  021-59883849(办公室)  64253756(实验室)

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传真: 021-59883730
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E-mail: taolm@ecust.edu.cn

地址:华东理工大学 实验十八楼1335室

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个人简介
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陶黎明,男,上海人,博士、教授、博士生导师,中国化工学会农药专业委员会委员、上海市优秀学科带头人、享受国务院政府特殊津贴专家、《农药学学报》编委等。历任上海市农药研究所课题组组长、研究室副主任、生物事业部部长,上海南方农药研究中心主任等。1982年于华东理工大学生物化学专业,获得工学学士学位,进入中国科学院武汉水生生物研究所工作。1987年于中国农科院研究生院昆虫生化专业,获得农学硕士学位,进入上海市农药研究所工作,1999年享受国务院特殊津贴,2001年评聘为教授级高级工程师,2008年上海市优秀学科带头人2005年于中国科学院上海生命科学院,获得理学博士学位,2010年调入华东理工大学药学院工作至今。近30年来,一直从事农药的筛选与研发,分别于1992年和1996年赴日本理化学研究所和德国巴斯夫公司从事农用生物活性物质研究;“八五” 至“十二五”期间主持和参与多项农药研究的国家科技攻关和科技支撑农药项目;参与完成973计划“绿色化学农药”项目中子课题研究;承担完成海洋863课题一项;承担完成上海市优秀学科带头人计划一项,获授权专利二十多项。

  

研究方向
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方向一: 生物农药的研发

开展以天然产物类农用抗生素的发现、研究与创制等方面为主的工作。

方向二: 农药毒理学

系统研究农药的作用方式、作用机理及代谢机制,重点开展杀虫剂的潜在作用靶标及对非靶标生物与环境生态的影响研究。


2010年调入我校以来的主要论著


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23Wenping Xu, Songlin Liu, Yang Zhang, Jufang Gao, Mingjun Yang, Xiao  Liu, Liming Tao*., Cypermethrin resistance conferred by  increased target insensitivity and metabolic detoxification in Culex pipiens  pallens Coq. Pesticide Biochemistry and  Physiology(2017),  http://dx.doi.org/10.1016/j.pestbp.2017.01.008.

22Yang Zhang, Jigang Wu, Wenping Xu, Jufang Gao, Haijing Cao, Mingjun  Yang, Bo Wang, Youwu Hao, Liming Tao*., Cytotoxic effects of  Avermectin on human HepG2 cells in vitro bioassays. Environmental  Pollution, 2017,220(Pt B):1127-1137.

21Yun Yang, Mimi Zong, Wenping Xu, Yang  Zhang, Bo Wang, Mingjun Yang,  Liming Tao*., Natural pyrethrins induces apoptosis in human  hepatocyte cells via Bax- and Bcl-2-mediated mitochondrial pathway,  Chemico-Biological  Interactions2017,262:38-45.

20Wenping Xu, Bo Wang, Mingjun Yang, Yang Zhang, Zhiping Xu, Yun Yang,  Haijing Cao, Liming Tao*.,Tebufenozide induces G1/S cell cycle  arrest and apoptosis in human cells. Environmental Toxicology and  Pharmacology, 2017,49:89 - 96.

19Youwu Hao, Gaohui Zhou, Wei Wu, Yang Zhang, Liming  Tao, Jianhua Yao, Wenping Xu*., Synthesis and antiviral evaluation of  novel N-6 substituted adenosine analogues. Tetrahedron  Letters, 2017, 58(3):190-193.

18Mingjun Yang, Bo Wang, Jufang Gao, Yang Zhang, Wenping Xu,  Liming Tao*. Spinosad induces programmed cell death involves  mitochondrial dysfunction and cytochrome c release in spodoptera frugiperda Sf9  cells. Chemosphere,  2017,169:155-161.

17Mingjun Yang, Guanggang Xiang, Diqiu Li, Yang Zhang, Wenping Xu,  Liming Tao*., The insecticide spinosad induces DNA damage and  apoptosis in HEK293 and HepG2 cells. Mutation Research/Genetic  Toxicology and Environmental  Mutagenesis2016,812:12-19.

16Yang Zhang, Mingming Luo, Wenping Xu, Mingjun Yang, Bo Wang, Jufang  Gao, Yaxiao Li, and Liming Tao*., Avermectin Confers Its  Cytotoxic Effects by Inducing DNA Damage and Mitochondria-Associated  ApoptosisJournal of Agricultural and Food  Chemistry, 2016, 64(36): 6895-6902.

15Zhiping Xu, Miaoqing Lu, Mingjun Yang, Wenping Xu, Jufang Gao, Yang  Zhang, Yun Yang, Liming Tao*., Pyrethrum-extract induced  autophagy in Insect cells: A new target? Pesticide Biochemistry and  Physiology  (2016),http://dx.doi.org/10.1016/j.pestbp.2016.09.003

14Xiaoqin Yu, Yang Zhang, Mingjun Yang, Junfu Guo, Wenping Xu, Jufang  Gao, Yaxiao Li, Liming Tao*., Cytotoxic effects of tebufenozide  in vitro bioassaysEcotoxicology and Environmental  Safety, 2016,129180-188.

13Yang Zhang, Songlin Liu, Xing Yang, Mingjun Yang, Wenping Xu, Yaxiao  Li, Liming Tao*., Staurosporine shows insecticidal activity  against Mythimna separataPesticide Biochemistry and Physiology,  2016,12837-44.

12Xiwei Wu, Lei Zhang, Chao Yang, Mimi Zong, Qingchun Huang*,  Liming Tao.Detection on emamectin benzoate induced apoptosis and DNA damage in  Spodoptera rugiperda Sf9 cell line.  Pesticide Biochemistry and Physiology, 2016, 126: 6–12.

11Diqiu Li, Qingchun Huang*Miaoqing Lu, Lei Zhang, Zhichuan Yang, Mimi Zong, Liming  Tao*.,The organophosphate insecticide chlorpyrifos confers its  genotoxic effects by inducing DNA damage and cell apoptosis.  Chemosphere2015, 135: 387–393.

10Diqiu Li, Xiwei Wu, Xiaoqin Yu, Qingchun Huang, Liming  Tao*.Synergistic effect of nonionic surfactants Tween 80 and  PEG6000 on  cytotoxicity of insecticides. Environmental Toxicology and  Pharmacology, 2015, 39: 677–682.

9Qingchun Huang*, Xiwei Wu, Xiaoqin Yu, Lei Zhang, Miaoqing Lu,  Liming Tao*., Comparison of the cytotoxic impact of  chlorfluazuron on selected insect and human cell lines.  Environmental Toxicology  Chemical.2015, 34(7): 1675-1682.

8Wenping Xu, Qingchun Huang*, Xiwei Wu, Xiaoqin Yu, Xuexiao  Wang, Liming Tao. Property of midgut a-amylase from Mythimna  separate Lepidoptera: Noctuidae) larvae and its responses to potential  inhibitors in vitro. Journal of Insect Science, 2014,  14(282); DOI:10.1093/jisesa/ieu144.

7Xiuyuan Zhuang, Daojing Zhang, Wen Qin, Jia Deng, Hui Shan,  Liming Tao* and Yuanguang Li*., A comparison on the preparation  of hot water extracts from Chlorella pyrenoidosa (CPEs) and radical scavenging  and macrophage activation effects of CPEs. Food & Function,  2014, 5(12):3252-3260.

6Xiang Guanggang, Li Diqiu, Yuan Jianzhong, Guan Jingmin, Zhai  Huifeng, Shi Mingan*, Tao Liming* Carbamate insecticide  methomyl confers cytotoxicity through DNA damage induction.  Food  and Chemical Toxicology,2013, 53,352-358.

5Wenping Xu, Daojing Zhang, Congcong Si, Liming  Tao*., ANTIFUNGAL MACROLIDES FROM Streptomyces cavourensis  YY01-17.Chemistry of Natural Compounds ,2013, 49(5),  988-989.

4Baoju Li, Huizhu Yuan, Jichao Fang, Liming  Tao, Qingchun Huang*, Xuhong Qian*, Zhijin Fan. Recent progress of  highly efficient in vivo biological screening for novel agrochemicals in China  .Pest Management Science,2010, 66 (3): 229 –  344

3Dao-jing Zhang, Gang Wei, Ying Wang, Cong-cong Si, Li Tian,  Li-ming Tao* and Yuan-guang Li. Bafilomycin K, a new antifungal  macrolide from Streptomyces flavotricini Y12-26. The Journal of  Antibiotics,2011, 64, 391–393.

2Dao-Jing Zhang, Rong-Feng Liu, Yuan-Guang Li*, Li-Ming  Tao, Li Tian. Two New Antifungal Cyclic Lipopeptides from Bacillus  marinus B-9987. Chemical & Pharmaceutical  Bulletin,2010, 58(12):1630-1634

1Rong-Feng Liu, Dao-Jing Zhang, Yuan-Guang Li*, Li-Ming  Tao, Li Tian*. A New Antifungal Cyclic Lipopeptides from Bacillus  marinus B-9987. Helvetica Chimica Acta,2010,  93(12):2419-2425.


网页发布时间: 2014-09-09