Contact Information

• Office: Room 1335, Researching Building 18

• Email: xuwp@ecust.edu.cn

• Office Phone: +86 21 64253756

• Office Fax: +86 21 59883730

Education

• 2009.06  Ph.D.  Microbiology, Nanjing Normal University, Nanjing, P. R. China

• 1989.06  B.E.  Biochemistry, East China University of Science&Technology, Shanghai, P. R. China

Group Members

Researchers:

Prof. Liming Tao, Dr. Yang Zhang,

Mr. Liang Cheng, Mr. Youwu Hao, Ms. Yun Yang, Mr. Yuanseng Chang, Mr. Hui Chen, Mr. Lei Ding, Ms. Ping Zhang, Ms. Yangyang Fan, Ms. Yutian Liu, Mr. Hongfei Ni, Mr.Wengtao Chen, Ms. Nan Zhang, Ms. Yandi Li, Ms. Shuang Han, Ms. Susu Wang

Research Interests

• Development of natural product pesticides  Engaged in the research and development of new green pesticides for microbial sources, and found natural products with biological activity of pesticides by screening microbial strains.

• Research of Biochemical technology  Engaged in biotransformation and biodegradation of pesticide active compounds by microbial strains

Professional Experience

• 2010-now  Shanghai Key Laboratory of Chemical Biology, East China University of Science and Technology

• 1989-2010  Shanghai Pesticide Research Institute

Publication from 2016 in ECUST:

1. Wenping Xu, Songlin Liu, Yang Zhang, Jufang Gao, Mingjun Yang, Xiao Liu, Liming Tao*., Cypermethrin resistance conferred by increased target insensitivity and metabolic detoxification in Culex pipiens pallens Coq. Pesticide Biochemistry and Physiology, 2017, 142C: 77-82.

2. Wenping Xu, Bo Wang, Mingjun Yang, Yang Zhang, Zhiping Xu, Yun Yang, Haijing Cao, Liming Tao*.,Tebufenozide induces G1/S cell cycle arrest and apoptosis in human cells. Environmental Toxicology and Pharmacology, 2017, 49:89 - 96.

3. Wenping Xu, Mingjun Yang, Jufang Gao, Yang Zhang, Liming Tao*. Oxidative stress and DNA damage induced by spinosad exposure in Spodoptera frugiperda Sf9 cells.Food and Agricultural Immunology, 2018, 29 :171-181.

4. WenwenGu¹, WenpingXu¹, Xiaoxi Sun, Bubing Zeng, ShuangjieWang, Nian Dong, Xu Zhang, ChengshuiChen, LongYang, Guowu Chen, AijieXin, Zhong Ni, JianWang, JunYang*.Anordrin Eliminates Tamoxifen Side Effects without Changing Its Antitumor Activity. Scientific Reports,2017, 7:439401-12.

5. Hong Liang¹, Wenping Xu¹, Jianping Chen, Huijuan Shi, Jiang Zhu, Xiaoqin Liu,Jian Wang*, Maohua Miao*, Wei Yuan. The Association between Exposure to Environmental Bisphenol A and Gonadotropic Hormone Levels among Men.PLOS ONE, 2017, 12:e01692171-12.

6. Youwu Hao, Gaohui Zhou, Wei Wu, Yang Zhang, Liming Tao, Jianhua Yao, Wenping Xu*., Synthesis and antiviral evaluation of novel N-6 substituted adenosine analogues. Tetrahedron Letters , 2017, 58:190-193.

7. Yang Zhang, Jigang Wu, Wenping Xu, Jufang Gao, Haijing Cao, Mingjun Yang, Bo Wang, Youwu Hao, Liming Tao*., Cytotoxic effects of Avermectin on human HepG2 cells in vitro bioassays. Environmental Pollution, 2017,220Pt B:1127-1137.

8. Yun Yang, Mimi Zong, Wenping Xu, Yang  Zhang, Bo Wang, Mingjun Yang, Liming Tao*., Natural pyrethrins induces apoptosis in human hepatocyte cells via Bax- and Bcl-2-mediated mitochondrial pathway, Chemico-Biological Interactions, 2017,262:38-45.

9. Mingjun Yang, Bo Wang, Jufang Gao, Yang Zhang, Wenping Xu,Liming Tao*. Spinosad induces programmed cell death involves mitochondrial dysfunction and cytochrome c release in spodoptera frugiperda Sf9 cells. Chemosphere, 2017,169:155-161.

10. Zhiping Xu, Miaoqing Lu, Mingjun Yang, Wenping Xu, Jufang Gao, Yang Zhang, Yun Yang, Liming Tao*., Pyrethrum-extract induced autophagy in Insect cells: A new target? Pesticide Biochemistry and Physiology,2017, 137: 21-26.

11. Mingjun Yang, Youwu Hao, Jufang Gao, Yang Zhang, Wenping Xu, Liming Tao*. Spinosad induces autophagy of Spodoptera frugiperda Sf9 cells and the activation of AMPK/mTOR signaling pathway. Comparative Biochemistry and Physiology, Part C, 2017, 195: 52-59.

12. Haijing Cao, Wenjing Liu, Yuansen Chang, Hui Chen, Yang Zhang, Wenping Xu, Liming Tao* 5′-Epi-SPA-6952A, a new insecticidal 24-membered macrolide produced by Streptomyces diastatochromogenes SSPRC-11339, Nature product research, http://dx.doi.org/10.1080/14786419.2017.1405401.

13. Yang Zhang, Yuansen Chang, Haijing Cao, Wenping Xu, Zhong Li,Liming Tao*.Potential threat of Chlorpyrifos to human liver cells via the caspase-dependent mitochondrial pathways.Food and Agricultural Immunology,2018, 29: 294-305.

14. Yang Zhang, Songlin Liu, Xing Yang, Mingjun Yang, Wenping Xu, Yaxiao Li, Liming Tao*., Staurosporine shows insecticidal activity against Mythimna separata．Pesticide Biochemistry and Physiology, 2016, 128: 37-44.  

15. Xiaoqin Yu, Yang Zhang, Mingjun Yang, Junfu Guo, Wenping Xu, Jufang Gao, Yaxiao Li, Liming Tao*., Cytotoxic effects of tebufenozide in vitro bioassays． Ecotoxicology and Environmental Safety, 2016, 129: 180-188.

16. Mingjun Yang, Guanggang Xiang, Diqiu Li, Yang Zhang, Wenping Xu, Liming Tao*. The insecticide spinosad induces DNA damage and apoptosis in HEK293 and HepG2 cells. Mutation Research/Genetic Toxicology and Environmental Mutagenesis, 2016, 812: 12-19.

17. Yang Zhang, Mingming Luo, Wenping Xu, Mingjun Yang, Bo Wang, Jufang Gao, Yaxiao Li, and Liming Tao*. Avermectin Confers Its Cytotoxic Effects by Inducing DNA Damage and Mitochondria-Associated Apoptosis. Journal of Agricultural and Food Chemistry, 2016, 64 (36): 6895-6902.