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杨武林

杨武林  副教授  博士生导师


E-mailyangwl@ecust.edu.cn

邮       200237

通讯地址上海市徐汇区梅陇路130号华东理工大学实验181121


教育背景

1. 2012.09–2017.09华东理工大学,药学专业博士,导师:邓卫平 教授

2. 2016.09–2017.08美国罗格斯大学国家公派联合培养博士生导师Daniel Seidel 教授

3. 2008.09–2012.07华东理工大学药物制剂专业学士

 

工作经历

1. 2021.09至今华东理工大学药学院,副教授,硕士生导师/博士生导师

2. 2019.12–2021.08华东理工大学药学院特聘副研究员,硕士生导师

3. 2017.10–2019.12华东理工大学药学院师资博士后合作导师李忠 教授

 

研究方向

1. 有机合成方法学

2. 农药化学生物学

3. 药物/农药绿色合成工艺开发


招生专业

1. 博士招生专业

    学术型博士:植物保护 (代码: 090400)

    学术型博士:制药工程与技术 (代码: 0817Z3)

    工程博士:生物与医药 (代码: 086000)

2. 硕士招生专业

    学硕:制药工程与技术 (代码: 0817Z3)

    学硕:植物保护 (代码: 090400)

    专硕:生物与医药 (代码: 086000)


【荣誉奖励

1. 上海市东方英才计划青年人才,2024年

2. 第十四届挑战杯”中国大学生创业计划竞赛国家级银奖 (第一指导教师)2024

3. 第十四届挑战杯中国大学生创业计划竞赛上海市金奖 (第一指导教师)2024

4. 华东理工大学第十四届挑战杯中国大学生创业计划竞赛“优秀指导教师”,2024

5. 中国化学会中化扬农农业化学新秀奖2023

6. 上海市青年科技启明星计划2023

7. 华东理工大学药学院科研之星,2023

8. 华东理工大学青年英才培育计划,2022

9. 上海产学研合作优秀项目奖三等奖 (排名第4)2021

10. 华东理工大学教学成果奖二等奖 (排名第6)2021

11. 上海市青年科技英才扬帆计划,2018

12. 上海市博士后日常工作经费资助,2017

13. 上海市优秀毕业生,2017


【科研项目

1. 国家自然科学基金面上项目 (22477027), 202501-202812, 负责人

2. 国家自然科学基金面上项目 (22171081), 202201-202512, 负责人

3. 国家自然科学基金青年基金 (21901072), 202001-202212, 负责人

4. 上海市青年科技启明星计划 (23QA1402600), 202304-202603, 负责人

5. 上海市自然科学基金面上项目 (23ZR1416700),  202304-202603, 负责人

6. 上海市农业科技创新春蕾项目 (沪农科T2023309),  202312-202612, 负责人

7. 上海市青年科技英才扬帆计划 (18YF1405600), 201805-202104, 负责人

8. 中国博士后科学基金特别资助 (2019T120310), 201906-201912, 负责人

9. 中国博士后科学基金面上资助 (2018M632037), 201806-201912, 负责人


代表性论文#共同第一作者, *通讯作者

  1.    Zhang Dongxu#, Zhou Cong#, Qi Suzhen, Zhang Huihui, Shao Xusheng, Xu Xiaoyong, Cheng Jiagao, Liu Zewen, Li Zhong, Yang Wu-Lin*. Discovery of Novel Neonicotinoids with Conjugated Diene Enabled by Cascade Allylation/Isomerization Synthetic Methodology. J. Agric. Food Chem., 2025, 73(5), 2784-2792.

  2.   Chen Yang#, Yan Hui#, Zheng Hanliang*, Deng Wei-Ping, Li Zhong, Yang Wu-Lin*. Ir/Brønsted acid dual-catalyzed asymmetric synthesis of bisbenzannulated spiroketals and spiroaminals from isochroman ketals. Org. Chem. Front., 2024, 11(20), 5831-5840.

  3.    Zhang Man#, Ru Yifan#, Wang Shilin, Fu Wen, Li Tianyu, Shao Xusheng, Li Zhong, Yang Wu-Lin*. Enantioselective synthesis of 2-amino-4H-chromene derivatives with antifungal activities on phytopathogenic fungi. Org. Chem. Front., 2024, 11(13), 3692-3699.

  4.    Hu Teng, Zhao Yuxuan, Luo Xiaoyan*, Li Zhong, Yang Wu-Lin*. Brønsted acid catalyzed [4 + 2] cycloaddition for the synthesis of bisbenzannulated spiroketals with antifungal activities. Org. Biomol. Chem., 2024, 22(23), 4656-4661.

  5.     Chen Diancong#, Zhang Man#, Zhang Dongxu#, Zhang Ziqi, Shao Xusheng, Xu Xiaoyong, Li Zhong, Yang Wu-Lin*. Iridium/Acid Dual-Catalyzed Enantioselective Aza-ene-type Allylic Alkylation of Nitro Ketene Aminals with Racemic Allylic Alcohols. Org. Lett., 2024, 26(2), 508-513.

  6. Liang Junqing#, Fu Wen#, Dong Lefeng, Zhou Cong, Yuan Qinglong, Chang Wenning, Yang  Wu-Lin*, Xu Xiaoyong, Shao Xusheng, Li Zhong*. N‑Difluoromethylthiophthalimide Reagents for Modular Synthesis of Diversified α‑Difluoromethylthiolated Ketones. Org. Lett.202325(26), 4797-4802.

  7. Yan Hui, Shao Xusheng, Xu Xiaoyong, Li Zhong*, Yang Wu-Lin*. Ir-Catalyzed Asymmetric Cascade Allylation/Spiroketalization Reaction for Stereoselective Synthesis of Oxazoline-Spiroketals. Org. Lett., 2023, 25(2), 325-330.

  8. Yan Hui, Zhang Man, Li Lin, Hu Teng, Yang Wu-Lin*. Advances in the Catalytic Asymmetric Synthesis of Chiral Spiroketals. Chin. J. Org. Chem., 2022, 42(11), 3640-3657.

  9. Yang Wu-Lin*, Shang Xin-Yu, Ni Tao, Yan Hui, Luo Xiaoyan, Zheng Hanliang*, Li Zhong, Deng Wei-Ping*. Diastereo- and Enantioselective Synthesis of Bisbenzannulated Spiroketals and Spiroaminals by Ir/Ag/Acid Ternary Catalysis. Angew. Chem. Int. Ed.2022, 61(42), e202210207.

  10. Yang Wu-Lin*, Shen Jia-Huan, Zhao Zeng-Hui, Wang Zhongao, Deng Wei-Ping*. Stereoselective Synthesis of Functionalized Azepines via Gold and Palladium Relay Catalysis. Org. Chem. Front., 2022, 9(17), 4685-4691.

  11. Yang Wu-Lin#*, Shang Xin-Yu#, Luo Xiaoyan, Deng Wei-Ping*. Enantioselective Synthesis of Spiroketals and Spiroaminals via Gold and Iridium Sequential Catalysis. Angew. Chem. Int. Ed.2022, 61(26), e202203661.

  12. Zhang Jian, Yang Wu-Lin*, Zheng Hanliang, Wang Yi, Deng Wei-Ping*. Regio- and Enantioselective γ-Allylic Alkylation of In Situ-Generated Free Dienolates via Scandium/ Iridium Dual Catalysis. Angew. Chem. Int. Ed.2022, 61(19), e202117079.

  13. Shen Jia-Huan#, Tian Fei#, Yang Wu-Lin*, Deng Wei-Ping*. Synergistic Copper and Chiral Lewis Base Catalysis for the Asymmetric Synthesis of Pyrrolo[1,2-a]indoles. Chin. J. Chem.2021, 39(12), 3292-3296.

  14. Yang Wu-Lin*, Wang Yuan-Lin, Li Wen, Gu Bu-Ming, Wang Si-Wen, Luo Xiaoyan, Tian Bo-Xue*, Deng Wei-Ping*. Diastereo- and Enantioselective Synthesis of Eight-Membered Heterocycles via an Allylation/Ring Expansion Sequence Enabled by Multiple Catalysis. ACS Catal., 2021, 11(20), 12557-12564.

  15. Yang Wu-Lin#*, Liu Tian-Tian#, Ni Tao, Zhu Bin, Luo Xiaoyan, Deng Wei-Ping*. Iridium-Catalyzed Asymmetric Cascade Allylation/Pictet-Spengler Cyclization Reaction for the Enantioselective Synthesis of 1,3,4-Trisubstituted Tetrahydroisoquinolines. Org. Lett., 2021, 23(7), 2790-2796.

  16. Zhang Jian, Gao Yan-Shan, Gu Bu-Ming, Yang Wu-Lin*, Tian Bo-Xue*, Deng Wei-Ping*. Cooperative N‑heterocyclic Carbene and Iridium Catalysis Enables Stereoselective and Regiodivergent [3 + 2] and [3 + 3] Annulation Reactions. ACS Catal.2021, 11(7), 3810-3821.

  17. Yang Wu-Lin#, Ni Tao#, Deng Wei‐Ping*. Iridium-Catalyzed Diastereo- and Enantioselective [4 + 3] Cycloaddition of 4‑Indolyl Allylic Alcohols with Azomethine Ylides. Org. Lett., 2021, 23(2), 588-594.

  18. Tian Fei#, Yang Wu‐Lin#*, Ni Tao, Zhang Jian, Deng Wei‐Ping*. Catalytic Asymmetric Dipolar Cycloadditions of Indolyl Delocalized Metal-allyl Species for the Enantioselective Synthesis of Cyclopenta[b]indoles and Pyrrolo[1,2-a]indoles. Sci. China Chem., 2021, 64(1), 34-40.

  19. Ye Chao#, Yang Wu‐Lin#, Zhai Yufei, Deng Hua, Luo Xiaoyan*, Kai Guoyin*, Deng Wei-Ping. Copper(I)-Catalyzed Asymmetric [3 + 3] Annulation Involving Aziridines to Construct Tetrahydro-β-carbolines. Org. Chem. Front.20207(21), 3393-3398.

  20. Yang Wu‐Lin#, Huang Zesheng#, Liu Yang‐Zi, Yu Xingxin*, Deng Wei‐Ping*. Highly Regio‐, Diastereo‐, and Enantioselective Assembly of Azepino[2,3‐b]indoles via Palladium‐Catalyzed [4 + 3] Cycloaddition. Chin. J. Chem., 2020, 38(12), 1571-1574.

  21. Tian Fei#, Zhang Jian#, Yang Wu-Lin*, Deng Wei-Ping*. Progress in Iridium-Catalyzed Asymmetric Allylic Substitution Reactions via Synergetic Catalysis. Chin. J. Org. Chem., 2020, 40(10), 3262-3278.

  22. Zhang Jian, Ni Tao, Yang Wu-Lin*, Deng Wei-Ping*. Catalytic Asymmetric [3 + 2] Annulation via Indolyl Copper-Allenylidene Intermediates: Diastereo- and Enantioselective Assembly of Pyrrolo[1,2-a]indoles. Org. Lett.2020, 22(11), 4547-4552.

  23. Yang Wu-Lin*, Li Wen, Yang Zhong-Tao, Deng Wei-Ping*. Organocatalytic Regiodivergent Ring Expansion of Cyclobutanones for the Enantioselective Synthesis of Azepino[1,2‑a]indoles and Cyclohepta[b]indoles. Org. Lett.2020, 22(10), 4026-4032.

  24. Zou Xue-Jie, Yang Wu-Lin*, Zhu Jing-Yan, Deng Wei-Ping*. Catalytic Enantioselective Formal Synthesis of MDM2 Antagonist RG7388 and Its Analogue. Chin. J. Chem., 2020, 38(5), 435-438.

  25. Zheng Xing, Sun Hao, Yang Wu-Lin*, Deng Wei-Ping*. Elaboration of Phosphoramidite Ligands Enabling Palladium-Catalyzed Diastereo- and Enantioselective All Carbon [4 + 3] Cycloaddition. Sci. China Chem., 2020, 63(7), 911-916.

  26. Zou Xuejie, Liu Yangzi, Shang Shaojing, Yang Wulin*, Deng Weiping*. Diastereoselective Synthesis of Functionalized Tetrahydro-γ-Carbolines via a [3 + 3] Cycloaddition of 2,2'-Diester Aziridines with β-(Indol-2-yl)-α,β-unsaturated Ketones. Chin. Chem. Lett.2020, 31(5), 1293-1296.

  27. Yang Wulin, Wang Hao, Pan Zirong, Li Zhong*, Deng Weiping. Asymmetric Synthesis of Pyrrolo[1,2-a]indoles via Organocatalytic [3 + 2] Annulation of Substituted 2-Vinylindoles with Azlactones. Chin. Chem. Lett.2020, 31(3), 721-724.

  28. Liu Yang-Zi, Wang Zhongao, Huang Zesheng, Zheng Xing, Yang Wu-Lin*, Deng Wei-Ping*. Palladium-Catalyzed Asymmetric [4 + 3] Cyclization of Trimethylenemethane: Regio-, Diastereo-, and Enantioselective Construction of Benzofuro[3,2-b]azepine Skeletons. Angew. Chem. Int. Ed.2020, 59(3), 1238-1242.