须志平 博士 副教授 硕士生导师
电话：021-64253979
办公室：实验十八楼1310A室
E-mail： zhipingxu@ecust.edu.cn
个人简介：
1998.09-2002.06 农学学士 南京农业大学 植物保护系
2002.09-2008.06 理学博士 南京农业大学 植物保护学院 农药系
2008.07-至今 华东理工大学 药学院 药物化工研究所
2015.09-2016.10 访问学者 美国 Kansas State University 昆虫系
研究方向：
ø 农药的生物评价及生理毒理研究：
1. 针对绿色化学农药的创制需求，建立多种靶标昆虫的活体和离体筛选模型，进行生物活性评价、药效分析和作用机制研究；
2. 借助细胞技术，利用昆虫细胞系和急性解离昆虫神经细胞，对新杀虫化合物和重要杀虫剂品种进行细胞毒理学研究；
ø 杀虫剂毒理学和害虫抗药性研究：
构建烟粉虱（CYP6CM1）和果蝇（CYP6G1）的细胞色素P450s体外表达系统，用于新型杀虫化合物和重要杀虫剂品种的代谢机理和交互抗性研究；
ø RNAi技术在害虫治理中的应用:
纳米滚环转录技术（RCT）在跳甲和鳞翅目害虫RNAi中的应用研究；
科研经历：
目前在领域内相关学术期刊参与发表22篇SCI学术论文，其中以第一作者或通讯作者发表学术论文10篇。主持国家自然科学基金青年基金1项 （31501674），完成中央高校基本科研业务费专项基金和上海市优秀青年教师基金各1项；先后参与农药领域国家重点研发计划、973计划、十二五国家科技支撑计划以及上海市科技支撑重点项目。参与申请发明中国专利8项，PCT专利3项，中国专利授权3项，美国授权专利1项，加拿大授权专利1项。
招生专业：
1. 学术学位硕士招生专业
植物保护（090400）农药毒理学方向
2. 专业学位硕士招生专业
生物与医药（制药工程0860）
发表部分论文：
[1] Zhiping Xu, Lianhua Zhu, Yun Yang, Yang Zhang, Miaoqing Lu, Liming Tao, Wenping Xu*. Bifenthrin induces DNA damage and autophagy in Spodoptera frugiperda Sf9 insect cells.In Vitro Cellular & Developmental Biology – Animal.2021, 57:264–271
[2] 吴嘉瑶, 梅倩倩, 吴勇超, 程家高*,李忠, 须志平*.新烟碱杀虫剂环氧虫啶对苜蓿蚜的毒力及其在苜蓿蚜和水稻中的降解转化. 植物保护学报，2019，46（2）：401-408.
[3] Zhiping Xu , Shen Li , Yujun Shen, Meijun Chen, Xusheng Shao*.Spiropyran-azobenzene-DBU system as solvent indicator. Tetrahedron Letters.2018, 59, 3829–3832
[4] Zhiping Xu*, Zhenhong Gao, Xusheng Shao*. Light-triggered release of insecticidally active spirotetramat-eno. Chinese Chemical Letters. 2018, 29，1648–1650
[5] Zhiping Xu, Miaoqing Lu, Mingjun Yang, Wenping Xu, Jufang Gao, Yang Zhang,Yun Yang, Liming Tao*. Pyrethrum-extract induced autophagy in insect cells: A new target?Pestic Biochem Physiol. 2017,137: 21-26.
[6] 吴勇超, 须志平*, 邵旭升, 程家高*, 李忠. 环氧虫啶对苜蓿蚜的毒力及对其体内解毒酶活性的影响[J]. 农药学学报 2016, 18(6): 710-716.
[7] Ziqian Zhang, Jiayao Wu, Zhihao Shang, Chao Wang, Jiagao Cheng,Xuhong Qian, Yi Xiao,*Zhiping Xu,* and Youjun Yang*. Photocalibrated NO Release from N‑Nitrosated Napthalimides upon One-Photon or Two-Photon Irradiation. Anal. Chem., 2016, 88, 7274-7280.
[8] Zhiping Xu, Lina Shi, Danping Jiang, Jiagao Cheng, Xusheng Shao*, Zhong Li. Azobenzene Modified Imidacloprid Derivatives as Photoswitchable Insecticides: Steering Molecular Activity in a Controllable Manner. Scientific Reports, 2015, 5, 13962.
[9] Baoyan Zhang, Zhiping Xu*, Yixi Zhang, Xusheng Shao, Xiaoyong Xu, Jiagao Cheng, Li Zhong. Fipronil induces apoptosis through caspase-dependent mitochondrial pathways in Drosophila S2 cells. Pestic Biochem Physiol. 2015, 119, 81-89.
[10] Xin Fang, Ying Tong Di, Yu Zhang, Zhi Ping Xu, Yang Lu, Qian Qian Chen, Qi Tai Zheng, and Xiao Jiang Hao*. Unprecedented Quassinoids with Promising Biological Activity from Harrisonia perforate. Angew. Chem. Int. Ed.2015, 54, 5592 –5595
[11] Ziqian Zhang, Baoyan Zhang, Xuhong Qian, Zhong Li, Zhiping Xu*, Youjun Yang*. Simultaneous Quantification of Hg2+ and MeHg+ in Aqueous Media with a Single Fluorescent Probe by Multiplexing in the Time Domain. Anal. Chem., 2014, 86, 11919-11924.
[12] Linlin Song, Zuhai Lei, Baoyan Zhang, Zhiping Xu*, Zhong Li* and Youjun Yang*. A Zero-Background Fluorescent Probe for Hg2+ Designed via the “Covalent-Assembly” Principle. Anal. Methods, 2014, 6, 7597–7600
[13] Siyuan Lu, Xusheng Shao, Zhong Li, Zhiping Xu*, Shishuai Zhao, Yinli Wu, and Xiaoyong Xu*. Design, Synthesis and Particular Biological Behaviors of Chain-opening Nitromethylene Neonicotinoids with cis-Configuration. J. Agric. Food Chem. 2012, 60(1), 322-330.
[14] Fengyi Liu§, Zhiping Xu§, Yu Cheng Zhu, Fangneng Huang, Yanhua Wang, Huiling Li, Hua Li, Congfen Gao, Weijun Zhou and Jinliang Shen*. Evidence of field-evolved resistance to Cry1Ac-expressing Bt cotton in Helicoverpa armigera (Lepidoptera: Noctuidae) in northern China. Pest Management Science, 2010, 66(2):155–161.
[15] Zhiping Xu, Fengyi Liu, Jin Chen，Fangneng Huang, David A Andow, Yanhua Wang, Yu Cheng Zhu and Jinliang Shen* . Using F2 screen to monitor frequency of resistance alleles to Bt cotton in field populations of Helicoverpa armigera (Hübner) (Lepidoptera: Noctuidae). Pest Management Science, 2009, 65:391-397.
[16] Fengyi Liu§, Zhiping Xu§, Juhua Chang, Jin Chen, Fenxia Meng, Yu Cheng Zhu, Jinliang Shen*. Resistance allele frequency to Bt cotton in field populations of Helicoverpa armigera (Hübner) (Lepidoptera: Noctuidae) in China. Journal of Economic Entomology,2008, 101(3): 933-943.
[17] Wang Yanhua, Gao Congfen, Xu Zhiping, Zhu Yu Chen, Lin Youwei, Dai Dejiang, Zhou Weijun, Shen Jinliang*. Buprofezin susceptibility survey, resistance selection and preliminary determination of resistance mechanism in Nilaparvata lugens (Homopetra: Delphacidae). Pest Management Science, 2008, 64(10):1050-1056.
[18] Yu Cheng Zhu, Fengyi Liu, Zhiping Xu, Juhua Chang, Jinliang Shen. F1 Screening for Resistance Gene Alleles to Bt Cotton in Helicoverpa armigera: How to Differentiate S and R Genotypes. J. Entomol. Sci. 2008. 43(3): 311-319.