鑱旂郴鏂瑰紡

E-mail: shaoxusheng@ecust.edu.cn

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瀛︽湳鍏艰亴

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銆�Chinese Chemical Letters銆嬮潚骞寸紪濮�

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涓浗鐭虫补涓庡寲瀛﹀伐涓氳仈鍚堜細浼樼鍑虹増鐗╁-鍥句功濂栦竴绛夊

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涓婃捣甯傜爺绌剁敓浼樼鎴愭灉鎸囧鏁欏笀

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鎷涚敓涓撲笟

鍒惰嵂宸ョ▼涓撲笟锛�鍗氬＋鐢熷甯�/纭曞＋鐢熷甯�

妞嶇墿淇濇姢涓撲笟锛�鍗氬＋鐢熷甯�/纭曞＋鐢熷甯�

鐢熺墿涓庡尰鑽伐绋嬩笓涓氾細宸ョ▼鍗氬＋瀵煎笀

瀛︽湳璁烘枃锛�2021-2025锛�

1.      Yiming Lu, Zhong Li, Xusheng Shao*, Peter Maienfisch*, Discovery of novel skeletons of aphid repellents based on the key fragment of nepetalactone and plant volatiles. Pest Manag. Sci. 2025,

2.      Zhubo Sheng, Wen Fu, Hangji Zhang, Weiguo Wang, Xiaoyan Li, Zhiping Xu, Xili Liu, Zhong Li, Xusheng Shao*. Light regulation of insect behavior by azobenzene-modified flonicamid as novel molecular tools. J. Agric. Food Chem. 2024, 72, 48, 26689鈥�26698.

3.      Wen Fu, Qinglong Yuan, Hangji Zhang, Xiaoyan Li, Yiming Lu, Wenming Yan, Yonghao Ye, Xili Liu, Zhong Li, Xusheng Shao*. Novel SDH inhibitors as antifungal leads: from azobenzene derivatives to the 1,2,4-oxadiazoles compounds. J. Agric. Food Chem. 2024, 2, 44, 24272鈥�24282.

4.      Lu Zhang, Zhenguo Zhang, Qiutang Huang, Chunqing Zhao, Xusheng Shao*, Zhong Li*. Design, Synthesis, and Insecticidal Activity of Novel meta-Diamide Compounds Bearing a Phthalimide as a Potential GABA Receptor Antagonist. J. Agric. Food Chem. 2024, 72, 48, 26626鈥�26632.

5.      Yifan Ru, Wen Fu, Sifan Guo, Xiaoyan Li, Cong Zhou, Zhiping Xu, Jiagao Cheng, Zhong Li, Xusheng Shao*. Discovery of novel nicotinamide derivatives by a two-step strategy of azo-incorporating and bioisosteric replacement.J. Agric. Food Chem. 2024, 72, 20794鈭�20804.

6.      Qi Xu, Hao Feng, Zhong Li, Xusheng Shao*. Acetyl-Coa carboxylase (ACC) proteolysis targeting chimeras (PROTACs): conceptual design and application as insecticide. J. Agric. Food Chem. 2024, 72, 18809-18815.

7.      Wen Fu, Zhubo Sheng, Zhi Qiao, Zhiping Xu, Meng Li, Ying Guan, Zhong Li, Xusheng Shao*. Optical control of insect behavior and receptors with azobenzene-bridged fipronil and imidacloprid. J. Agric. Food Chem. 2024, 72, 12469-12477.

8.      Qinglong Yuan, Wen Fu*, Xiaoyan Li, Zhiping Xu, Xili Liu, Zhong Li, Xusheng Shao*. Design, synthesis, bioactivity, and tentative exploration of action mode for benzyl ester-containing derivatives.J. Agric. Food Chem. 2024, 72, 16112-16127.

9.      Wensong Qi, Yiming Lu, Xusheng Shao*, Peter Maienfisch*, Effects of natural ionones and derived novel analogues with simplified structures on behavioral responses of whiteflies. Pest Manag. Sci. 2024, 2024, 80, 4523-4532.

10.    Qi Yin, Wen Fu, Xinyue Hu, Zhiping Xu, Jiagao Cheng, Zhong Li, Xusheng Shao*.Application of TNB in dual photo-controlled release of phenamacril, imidacloprid and imidacloprid synergist. Photochem. Photobiol., 2024, 100, 1813鈥�1826.

11.    Yiming Lu, Zhong Li, Xusheng Shao*, Peter Maienfisch*, Discovery and Properties of Novel Analogues of the Aphid Pheromones Nepetalactone and Nepetalactol, Pest Manag. Sci. 2024, 80, 2773-2784.

12.    Wen Fu, Zhongli Shao, Zhiping Xu, Zhong Li, Xusheng Shao*. O-nitrobenzyl Caged Molecule Enables Photo-controlled Release of Thiabendazole. ChemBioChem 2024,25, e202300742.

13.    Du Tan, Xiaoyong Xu, Zhong Li, Zhiping Xu*, Xusheng Shao*. Design, Synthesis, and Synergistic Activities of Eight-Membered 1Carbon Bridged Neonicotinoid Derivatives. Chem. Biodiversity 2024, 21, e202301412.

14.    Ziyi Wei, Weiguo Wang, Wenping Xu, Liming Tao, Zhong Li, Yang Zhang, Xusheng Shao*. Studies on immunotoxicity induced by emamectinbenzoate in zebrafish embryos based on metabolomics Environ. Toxicol. 2024, 39, 97-105.

15.    Qi Xu, Chao Zhang, Zhiping Xu; Long Wang, Zewen Liu, Zhong Li, Xusheng Shao*. Optical Control of Invertebrate nAChR and Behaviors with Dithienylethene-Imidacloprid, J. Agric. Food Chem. 2023, 71, 11048-11055.

16.    Wen Fu, Xusheng Shao*. Application of Photopharmacology in Agrochemicals. Advanced Agrochem, 2023, 2, 142-153.

17.    Ziyi Wei, Weiguo Wang, Hao Feng, Wenping Xu, Liming Tao, Zhong Li, Yang Zhang, Xusheng Shao*. Investigation on the immunotoxicity induced by Emamectin Benzoate on THP-1 macrophages based on metabolomics analysis. Environ. Toxicol. 2023, 38, 1053-1062.

18.    Qinglong Yuan, Yongchao Zhang, Shaoqing Du, Wen Fu, Zhiping Xu, Jiagao Cheng, Zhong Li, Xusheng Shao*. Design, Synthesis, and Biological Activity of Heterocyclic Methyl Esters. J. Heterocycl. Chem. 2023, 60, 781-791.

19.    Xiaoyi Dai, Zhong Li, Xusheng Shao*. Photo-controlled Release of Carbendazim from Photocaged Molecule. Photochem. Photobiol., 2023, 99, 1310-1317.

20.    Wen, Fu, Kang Du, Zhiping Xu; Jiagao Cheng, Zhong Li, Xusheng Shao*. Dual Photo-controlled Release System for Fipronil and Dinotefuran, Photochem. Photobio. Sci. 2023, 22, 825-836.

21.    Qingqing Hou, Qiutang Huang, Qi Xu, Cong Zhou, Yaoyao Du, Yunfan Ji, Zhiping Xu; Jiagao Cheng, Zhong Li, Chunqing Zhao, Xusheng Shao*. Synthesis and activity-detection of photoswitchable ligands with fipronil to insect, Pest Manag. Sci. 2023, 79, 1086-1093.

22.    Wen Fu, Xinyue Hu, Qinglong Yuan, Zhiping Xu, Jiagao Cheng, Zhong Li, Xusheng Shao*. Design, Synthesis and Bioassay of the Emerging Photo-responsive Fungicides. Chin. Chem. Lett. 2023, 34, 108064.

23.    Ziyi Wei, Weiguo Wang, Wen Fu, Ping Zhang, Hao Feng, Wenping Xu, Liming Tao, Zhong Li, Yang Zhang, Xusheng Shao*. The potential immunotoxicity of Emamectin Benzoate on the human THP-1 macrophages. Environ. Toxicol. 2023, 38, 500-510.

24.    Lu Zhang, Yijin Kong, Xusheng Shao*, Zhong Li*. Design, Synthesis, and Insecticidal Activities of Novel N-Pyridylpyrazole Amide Derivatives Containing a Maleimide. Chem. Biodivers. 2023, 20, e202300237.

25.    Wen, Fu, Yunfan Ji, Yanan Zhang; Jiazheng Xu, Zhiping Xu; Jiagao Cheng, Zhong Li, Xusheng Shao*. Optical Regulation of Sodium Channels by the Azobenzene Pyrethrins. ACS Agric. Sci. Technol. 2022,2, 1311鈥�1317.

26.    Zhi Qiao, Wen Fu, Qiu-Tang Huang, Zhong Li, Chunqing Zhao, Xusheng Shao*. Optical regulation of GABA Receptor by Visible Light via Azobenzene-Phenylpyrazole. J. Agric. Food Chem. 2022, 70, 5541-5550.

27.    Meijun Chen, Zhong Li, Xusheng Shao*, Peter Maienfisch*. Bioisosteric Replacement driven Lead Optimization of Tyclopyrazoflor. J. Agric. Food Chem. 2022, 70, 11123鈥�11137.

28.    Meijun Chen, Zhong Li, Xusheng Shao*, Peter Maienfisch*. Scaffold-Hopping Approach to Identify New Chemotypes of 2 Dimpropyridaz, J. Agric. Food Chem. 2022, 70, 11109鈥�11122.

29.    Wen Fu, Zhongli Shao, Xujuan Sun, Cong Zhou, Zhiping Xu, Yang Zhang, Jiagao Cheng, Zhong Li, Xusheng Shao*.Reversible Regulation of Succinate Dehydrogenase by tools of Photopharmacology. J. Agric. Food Chem. 2022, 70, 4279-4290.

30.    Zhi Qiao, Yunfan Ji, Yongchao Zhang, Zhong Li, Zhiping Xu, Xusheng Shao*. Azobenzene-Isoxazoline as photopharmacological ligand for optical control of insect GABA receptor and behavior. Pest Manag. Sci. 2022, 78, 467-474.

31.    Zhi, Qiao, Wen Fu, Yongchao Zhang, Ruijia Chen, Zhiping Xu, Zhong Li, Xusheng Shao*. Azobenzene-Semicarbazone Enables Optical Control of Insect Sodium Channel and Behavior锛�J. Agric. Food Chem. 2021, 51, 15554-155561.

32.    Shaoqing Du, Qinglong Yuan, Xueping Hu, Wen Fu, Qi Xu, Ziyi Wei, Jiazheng Xu, Xusheng Shao*, Xuhong Qian*. Synthesis and Biological Activity of Novel Antifungal Leads: 3,5-Dichlorobenzyl Ester Derivatives. J. Agric. Food Chem. 2021, 69, 15521-15529.

33.    Yaoyao Du, Zhongli Shao, Qi Xu, Zhong Li, Xusheng Shao*.Azobenzene-Avermectin B1a Derivatives for Optical Modulation of Insect Behaviors. J. Agric. Food Chem. 2021, 69, 15530-15537.

34.    Wen Fu, Qinglong Yuan, Xinyue Hu, Xujuan Sun, Zhiping Xu, Yang Zhang, Jiagao Cheng, Yonghao Ye, Zhong Li, Xusheng Shao*. Azo-incorporating Increases Inhibitory Activity of Succinate Dehydrogenase. J. Agric. Food Chem. 2021, 69, 13448-13459.

35.    Qi Xu, Hao Feng, Xusheng Shao*. Light-induced Activities of Novel Naphtho[1,8-ef]isoindole-7,8,10(9H)-trione and Oxoisoaporphine Derivatives towards Mosquito Larvae. Bioorg. Med. Chem. Lett. 2021, 48, 128225-128231.

36.    Qi Xu, Yunfan Ji, Meijun Chen, Xusheng Shao*. 4-Hydroxyl-oxoisoaporphine, one small molecule as theranostic agent for simultaneous fluorescence imaging and photodynamic therapy as type II photosensitizer. Photochem. Photobio. Sci. 2021, 20, 501-512.

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7.      閭垫棴鍗�锛屾潕蹇狅紝浠樼ǔ锛岀▼瀹堕珮锛屽緪鏅撳媷锛岄』蹇楀钩. 涓撳埄鍚嶇О: 鍋舵爱鑻被鏉傜幆閰拌兒琛嶇敓鐗╁強鍏跺埗澶囨柟娉曞拰搴旂敤锛屼笓鍒╃敵璇峰彿锛�CN2019113829608锛岀敵璇锋椂闂达細2019骞�12鏈�27鏃�. 鍏紑鍙凤細CN 111087345 A 锛屽叕寮€鏃ワ細2020骞�5鏈�1鏃ャ€�鎺堟潈鍙凤細ZL202010280529.9銆傛巿鏉冨叕鍛婃棩锛�2024骞�10鏈�15鏃ャ€�

8.      閭垫棴鍗�锛�鏉庡繝锛屾潨鐟剁懚锛岀▼瀹堕珮锛屽緪鏅撳媷锛岄』蹇楀钩. 涓撳埄鍚嶇О: 鍋舵爱鑻被闃跨淮鑿岀礌琛嶇敓鐗╁強鍏跺埗澶囨柟娉曞拰搴旂敤锛屼笓鍒╃敵璇峰彿锛�CN2020100755670锛岀敵璇锋椂闂达細2020骞�1鏈�22鏃�. 鍏紑鍙凤細CN113150053A 锛屽叕寮€鏃ワ細2021骞�7鏈�23鏃ャ€�鎺堟潈鍙凤細ZL202010075567.0銆傛巿鏉冨叕鍛婃棩锛�2024骞�10鏈�01鏃ャ€�

9.      閭垫棴鍗�锛屾潕蹇狅紝寮犳案瓒咃紝绋嬪楂橈紝寰愭檽鍕囷紝椤诲織骞�. 鍚″攽閰拌兒绫诲寲鍚堢墿鍙婂叾鍒跺鏂规硶鍜屽簲鐢紝涓撳埄鐢宠鍙凤細CN2021107380603锛岀敵璇锋椂闂达細2021骞�6鏈�30鏃�. 鍏紑鍙凤細CN115536586A锛屽叕寮€鏃ワ細2022骞�12鏈�30鏃ャ€�鎺堟潈鍙凤細ZL202110738060.3銆傛巿鏉冨叕鍛婃棩锛�2024骞�8鏈�9鏃ャ€�

10.   閭垫棴鍗�锛屾潕蹇狅紝涔旀不锛屼警鏅存櫞锛岀▼瀹堕珮锛屽緪鏅撳媷锛岄』蹇楀钩. 涓撳埄鍚嶇О: 鍚伓姘粨鏋勭殑鑻熀鍚″攽绫诲寲鍚堢墿鍙婂叾鍒跺鏂规硶鍜屽簲鐢紝涓撳埄鐢宠鍙凤細CN2019113664094锛岀敵璇锋椂闂达細2019骞�12鏈�26鏃�. 鍏紑鍙凤細CN111072568 A锛屽叕寮€鏃ワ細2020骞�4鏈�28鏃ャ€�鎺堟潈鍙凤細ZL201911366409.4銆傛巿鏉冨叕鍛婃棩锛�2024骞�7鏈�23鏃ャ€�

11.   閭垫棴鍗�锛�鏉庡繝锛屽緪鐞紝绋嬪楂橈紝寰愭檽鍕囷紝椤诲織骞�. 涓撳埄鍚嶇О: 鍋舵爱鑺冲熀鑴茬被琛嶇敓鐗╁強鍏跺埗澶囨柟娉曞拰搴旂敤锛屼笓鍒╃敵璇峰彿锛�CN2020101506872锛岀敵璇锋椂闂达細2020骞�3鏈�6鏃�. 鍏紑鍙凤細CN 111217722 A 锛屽叕寮€鏃ワ細2020骞�6鏈�2鏃ャ€�鎺堟潈鍙凤細ZL 2020 1 0280529.9銆傛巿鏉冨叕鍛婃棩锛�2024骞�01鏈�01鏃ャ€�

12.   閭垫棴鍗�锛�鏉庡繝锛屼警鏅存櫞锛岄』蹇楀钩锛屽緪鏅撳媷锛岀▼瀹堕珮. 涓撳埄鍚嶇О: 浜岃姵鍩轰箼鐑被鍖栧悎鐗╁強鍏跺埗澶囧拰鐢ㄩ€�, 涓撳埄鐢宠鍙凤細CN201810694476.8锛岀敵璇锋椂闂达細2018骞�6鏈�29鏃�. 鍏紑鍙凤細CN 110655512 A锛屽叕寮€鏃ワ細2020骞�1鏈�7鏃ャ€�涓撳埄鎺堟潈鍙凤細ZL201610815058.0锛屾巿鏉冩椂闂达紝2023骞�2鏈�28鏃ャ€�

13.   閭垫棴鍗�锛屾潕蹇狅紝寮犺秴锛岀▼瀹堕珮锛屽緪鏅撳媷锛岄』蹇楀钩. 涓撳埄鍚嶇О: 涓€绉嶄簩鑺冲熀涔欑儻绫诲彲鍏夎嚧鍙樿壊鏉€铏寲鍚堢墿鍙婂叾鍒跺鏂规硶鍜岀敤閫�, 涓撳埄鐢宠鍙凤細CN201610815058.0锛岀敵璇锋椂闂达細2016骞�9鏈�9鏃�. 涓撳埄鍏紑鍙凤細CN106397419A锛屽叕寮€鏃堕棿锛�2017骞�2鏈�15鏃ャ€�涓撳埄鎺堟潈鍙凤細ZL20181 0694476.8锛屾巿鏉冩椂闂达紝2019骞�6鏈�25鏃ャ€�

14.   閭垫棴鍗�锛�鏉庡繝锛岄檲鍗楅槼锛屽緪鏅撳媷锛岄』蹇楀钩锛岀▼瀹堕珮. 涓撳埄鍚嶇О: 鍥涙阿鑼氬苟鍚″挴骞跺挭鍞戠殑琛嶇敓鐗╁強鍏跺埗澶囨柟娉曞拰鐢ㄩ€�, 涓撳埄鐢宠鍙凤細CN201410181612.5锛岀敵璇锋椂闂达細2014.04.30. 涓撳埄鍏紑鍙凤細CN105017257A锛屽叕寮€鏃堕棿锛�2015骞�11鏈�4鏃ャ€�鎺堟潈鍙凤細ZL201410181612.5锛屾巿鏉冩椂闂达細2017骞�5鏈�24鏃ャ€�

鎾板啓涔︾睄

1.      涓浗妞嶇墿淇濇姢鐧剧鍏ㄤ功锛屼腑鍥芥灄涓氬嚭鐗堢ぞ锛�2022骞�6鏈堬紝 ISBN锛�978-7-5219-0968-5銆�

2.      鍐滆嵂涓撲笟鑻辫锛岀紪鍐欎汉鍛橈紝鏅€氶珮绛夋暀鑲插啘鏉戝啘涓氶儴鈥�鍗佷笁浜�鈥�瑙勫垝鏁欐潗锛屽寲瀛﹀伐涓氬嚭鐗堢ぞ锛�2021骞�4鏈堬紝ISBN 978-7-122-38643-4銆�

3.       Xusheng Shao. Photoresponsive pesticidal agents. (Chapter 18), P297-310. Recent highlights in the discovery and optimization of crop protection products. ISBN 9780128210352, 2021.03.26, Elsevier, London.ISBN: 978-0-12-821035-2.

4.       Xusheng Shao, Zhong Li, Xuhong Qian. Research and development of green pesticide in China (Chapter 5), P39-64. Recent highlights in the discovery and optimization of crop protection products. ISBN 9780128210352, 2021.03.26, Elsevier, London.

5.      鏉庡繝, 閭垫棴鍗�銆備腑鍥藉啘鑽爺绌朵笌搴旂敤鍏ㄤ功-鍐滆嵂鍒涙柊锛�鍖栧宸ヤ笟鍑虹増绀�锛屽寳浜紝鍑虹増鏃ユ湡锛�2019骞�11鏈�1鏃ワ紱ISBN978-7-122-33892-1銆�

6.      Xusheng Shao, Xuhong Qian, Xiaoyong Xu, Zhong Li, Philip W. Lee. Current situation for research and development of novel pesticides in China. In Trend in Pesticide Discovery Research-Development of Safer and Environmentally Friendly Pesticides. Noriharu Umetsu, eds. 2018. (Book Chapter) , 鍑虹増鏃ユ湡锛�2018骞�3鏈�30鏃ワ紱鏃ユ湰娴锋磱鏂囧寲鏍紡浼氱ぞ锛�Noriharu Umetsu銆�