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周聪 特聘副研究员 硕士生导师

山东临沂人


E-mailzhoucong@ecust.edu.cn

通讯地址:  上海市徐汇区梅陇路130号华东理工大学实验18531

  上海市奉贤区海思路999号华东理工大学实验5403


硕士招生专业

学硕:植物保护(090400


研究方向

绿农药创制;AI辅助的农药分子设计


教育背景

1.  201909-202212月,华东理工大学,农药学,博士,导师:程家高 教授,Peter Maienfisch 教授

2.  201609-201906月,华东理工大学,药学,硕士,导师:程家高 教授

3.  201209-201606月,青岛科技大学,药物制剂,学士

 

工作经历

1.  202501-至今,华东理工大学,药学院,特聘副研究员,硕士生导师

2.  202301-202412月,华东理工大学,药学院,博士后,合作导师:钱旭红 教授


荣誉奖励

1.  国家资助博士后研究人员计划,2023

2.  上海市“超级博士后”激励计划,2023

3.  上海市优秀毕业生,2023


主持科研项目

1.  国家自然科学基金青年基金(22307039),20241-202612

2.  中国博士后科学基金面上项目(2023M731089),20237-202412

3.  上海市农业科技创新春蕾项目(沪农科T2024302),202411-202710

4.  上海市教育委员会“AI赋能科研计划20251-202612


发表论文#为共同一作

1.   Dongxu Zhang#, Cong Zhou#, Suzhen Qi, Huihui Zhang, Xusheng Shao, Xiaoyong Xu, Jiagao Cheng, Zewen Liu, Zhong Li, Wu-Lin Yang, Discovery of novel neonicotinoids with conjugated diene enabled by cascade allylation/isomerization synthetic methodology. J. Agric. Food Chem. 2025, 73, 2784–2792.一区TOP

2.   Cong Zhou#, Yijin Kong#, Huihui Zhang, Na Zhai, Zhong Li, Xuhong Qian, Zewen Liu*, and Jiagao Cheng* Computational modeling-oriented substructure splicing application in the identification of thiazolidine derivatives as potential low honeybee toxic neonicotinoids J. Agric. Food Chem. 2024, 72, 11968–11979. 一区TOP

3.   Liangliang Cheng#, Cong Zhou#, Qinglong Yuan, Letian Zhang, Xusheng Shao, Xiaoyong Xu, Zhong Li, Jiagao Cheng* 3D-QSAR model-oriented optimization of Pyrazole β-Ketonitrile derivatives with diphenyl ether moiety as novel potent succinate dehydrogenase inhibitors. Pest Manag. Sci., 2024, 80, 5299–5306.一区TOP

4.   Yijin Kong#, Cong Zhou#, Du Tan, Xiaoyong Xu, Zhong Li, and Jiagao Cheng* Discovery of potential neonicotinoid insecticides by an artificial intelligence generative model and structure-based virtual screening. J. Agric. Food Chem. 2024, 72, 5145–5152.一区TOP

5.   Cong Zhou, Guanglong Li, Sihui Wang, Zhong Li, Xuhong Qian, and Jiagao Cheng* Novel insecticidal benzo[4,5]imidazo[1,2-b]pyrazole derivatives identified through ring-closure scaffold hopping on fipronil. Chem. Biodivers. 2024, e202402148.

6.   Xiaoyang Li#, Cong Zhou#, Wulin Yang, Zhong Li, and Jiagao Cheng* Novel insecticidal pyridylhydrazono derivatives identified via scaffold hopping and conformation regulation strategies. Chem. Biodivers. 2024, e202401767.

7.   Xiaoyang Li#, Cong Zhou#, Lujue He, Zhiping Xu, Zhong Li, and Jiagao Cheng* Identification of potential novel insect TRPV channel modulators by homology modeling, binding mode analysis, virtual screening studies and chemical optimization. New J. Chem., 2024, 48, 12688-12696.

8.   Cong Zhou, Zhong Li, Xuhong Qian, Jiagao Cheng*, and Peter Maienfisch* Novel acaricidal silico-containing pyrazolyl acrylonitrile derivatives identified through rational carbon−silicon bioisosteric replacement strategy. J. Agric. Food Chem. 2023, 71, 18239–18249.一区TOP

9.   Cong Zhou, Xujuan Sun, Wen Fu, Zhong Li, Jiagao Cheng*, and Peter Maienfisch*Rational exploration of novel SDHI fungicide through amide-β-ketonitrile bioisosteric replacement strategy. J. Agric. Food Chem. 2023, 71, 5483–5495.一区TOP

10. Cong Zhou, Xin Wang, Xiaocao Quan, Jiagao Cheng*, Zhong Li, and Peter Maienfisch*.Silicon-containing complex II acaricides-design, synthesis, and pharmacological optimization. J. Agric. Food Chem. 2022, 70, 11063–11074.一区TOP

11. Cong Zhou, Jiagao Cheng*, Ryan Beadle, Fergus G Earley, Zhong Li, Peter Maienfisch*.Design, synthesis and acaricidal activities of Cyflumetofen analogues based on carbon-silicon isosteric replacement. Bioorgan. Med. Chem2020, 28, 115509.

12. Ting Li#, Cong Zhou#, Nan Zheng, Hongbin Yang, Guanglin Kuang, Xusheng Shao, Zhong Li, Jiagao Cheng*. Insights into the synergistic mechanism of target resistance: A case study of N. lugens RDL-GABA receptors and fipronil. Biophys. Chem.2020, 265, 106426.


申请专利

1.   (中国发明专利授权)程家高,Peter Maienfsch周聪,李忠,邵旭升,徐晓勇,钱旭红. 含硅酰基乙腈化合物及其制备方法与应用. 专利号 ZL 201910415131.9. 授权日:2021-02-09

2.   (中国发明专利授权)程家高,Peter Maienfsch周聪,李忠,邵旭升,徐晓勇,钱旭红. 硅丙烯腈类化合物及其制备方法与应用. 专利号 ZL 202011460379.6. 授权日:2024-10-25

3.   (国际发明专利公开)程家高,Peter Maienfsch周聪,李忠,邵旭升,徐晓勇,钱旭红. 硅丙烯腈类化合物及其制备方法与应用. 公开号 WO 2022121908 A1. 公开日2022-06-16

4.   (中国发明专利公开)程家高,周聪Peter Maienfsch,李忠,邵旭升,徐晓勇,钱旭红. 酮腈类化合物及其制备方法与应用. 公开号 CN 117658935 A. 公开日2024-03-08.

5.   (中国发明专利公开)程家高,程亮亮,周聪,李忠,邵旭升,徐晓勇,钱旭红. 一种长链酮腈类化合物及其制备方法与应用. 公开号 CN 119462506 A 公布日2025-02-18

6.   (中国发明专利申请)程家高,周聪,李晓阳,王丛,吴彪,孙绪娟,李忠,邵旭升,徐晓勇,钱旭红. 一种硫酯类化合物及其制备方法与应用. 申请号:202510087352.3